Androgen-Responsive Genes in Prostate Cancer: Regulation, Function and Clinical Applications

by Zhou Wang

Book Overview

Androgens and androgen receptors (AR) play critical roles in the development and progression of prostate cancer, the most frequently diagnosed cancer and second leading cause of cancer death in US males. AR is an androgen-dependent DNA-binding transcription factor that regulates the expression of androgen-responsive genes. Identification and characterization of androgen-responsive genes provide insights into the cellular mechanisms of androgen action...

• Format: Paperback
• Language: English
• ISBN: 1489986871
• ISBN13: 9781489986870
• Release Date: February 2015
• Publisher: Springer
• Length: 348 Pages
• Weight: 1.11 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"