Androgen Action in Prostate Cancer

by Donald Tindall

Book Overview

Androgens are critical regulators of prostate differentiation and function, as well as prostate cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the androgen receptor (AR), a nuclear receptor transcription factor. Historically, the gene expression program mediated by the AR has been poorly understood. However, recent...

• Format: Hardcover
• Language: English
• ISBN: 0387691774
• ISBN13: 9780387691770
• Release Date: May 2009
• Publisher: Springer
• Length: 826 Pages
• Weight: 2.80 lbs.
• Dimensions: 1.7" x 6.3" x 9.3"