Aging of the Genome: The Dual Role of DNA in Life and Death

by Jan Vijg

Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting...

• Format: Hardcover
• Language: English
• ISBN: 019856922X
• ISBN13: 9780198569220
• Release Date: March 2007
• Publisher: Oxford University Press, USA
• Length: 384 Pages
• Weight: 2.24 lbs.
• Dimensions: 1.0" x 7.4" x 9.9"