Age and Susceptibility to Toxic Substances

by Edward J. Calabrese

Investigates the relationship between age and environmentally induced diseases, which must be taken into consideration in establishing acceptable exposure standards for high-risk groups in society. Assesses the effect of age on gastrointestinal and dermal absorption of toxic substances and drugs, and age differences in plasma protein binding and xenobiotic metabolism. Contains several chapters on organ-specific toxicity differences according to age. Also discusses genotoxicity and environmentally induced cancer. A final chapter synthesizes the information and addresses the relevance of this knowledge to biological basis of safety considerations.

• Format: Hardcover
• Language: English
• ISBN: 0471843660
• ISBN13: 9780471843665
• Release Date: September 1986
• Publisher: Wiley-Interscience
• Length: 296 Pages
• Weight: 1.24 lbs.