Actin-Binding Proteins and Disease

by Deepak Chhabra

Book Overview

Actin is a ubiquitous protein present in high concentrations in virtually all cells. It's assembly and disassembly is modulated by more than 100 actin-binding proteins. These interactions are essential for a variety of important cellular processes including cell division, gene expression and motility.

There are scattered reports in the published literature citing relationships between actin, actin-binding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders.

This volume is relevant to a wide readership including cell biologists interested in understanding how structural and functional changes in proteins impact on the organism as a whole. Additionally, clinicians will be interested because the book explains the role of cytoskeletal proteins in various diseases, including cancer and immune system disorders.

• Format: Paperback
• Language: English
• ISBN: 1441924531
• ISBN13: 9781441924537
• Release Date: November 2010
• Publisher: Springer
• Length: 348 Pages
• Weight: 1.18 lbs.
• Dimensions: 0.8" x 9.2" x 6.1"