Dr. Jim Bob Brady is attempting a difficult knee reconstruction on Melvin Brown, Houston philanthropist and University Hospital board member, when Doc is notified that his wife Mary Louise has been involved in a near-fatal hit-and-run. When Brady arrives at his wife's bedside, he sees the horrific aftermath of the crash, including the worst, a brain injury. He calls for help from all his colleagues, and most importantly from his long-term friend-and...