The centerpiece of the thesis is the search for muon neutrino to electron neutrino oscillations which would indicate a non-zero mixing angle between the first and third neutrino generations (θ13), currently the "holy grail" of neutrino physics. The optimal extraction of the electron neutrino oscillation signal is based on the novel "library event matching" (LEM) method which Ochoa developed and implemented together with colleagues at Caltech...