Due to the widespread use of heterocyclic molecules in biological, medicinal, and pharmaceutical fields, the aim of the present work has been directed toward building of new molecules containing active moieties of different heterocyclic ring starting from 5-nitro isatin.❖Synthesis of new spiro four membered heterocyclic rings of 3-(substituted phenylimino)-5-nitro indole-1H-2-one includes: spiro 1,3-diazetidine-2-one and spiro 2-thio-1,3-diazetidine.❖Synthesis...